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Ligand

NameCYPROHEPTADINE
Molecular formulaC21H21N
IUPAC name1-methyl-4-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,9,11,13-heptaenylidene)piperidine
Molecular weight287.406
Hydrogen bond acceptor1
Hydrogen bond donor0
XlogP4.7
SynonymsPeriactin
Eiproheptadine
129-03-3
Dronactin
Periactinol
[ Show all ]
Inchi KeyJJCFRYNCJDLXIK-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3
PubChem CID2913
ChEMBLCHEMBL516
IUPHAR277
BindingDB50017721
DrugBankDB00434

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 47
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
1522055-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1522135-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1522065-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
1522255-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1521835-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
1522025-hydroxytryptamine receptor 2AQ75Z89HTR2ABos taurus (Bovine)470
1522075-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1522085-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
5560525-hydroxytryptamine receptor 2BQ02152Htr2bMus musculus (Mouse)479
1521985-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
1522115-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1522225-hydroxytryptamine receptor 2CP34968Htr2cMus musculus (Mouse)459
1521895-hydroxytryptamine receptor 5BP35365Htr5bRattus norvegicus (Rat)370
1521995-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
1522095-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
1521925-hydroxytryptamine receptor 7P50407HTR7Cavia porcellus (Guinea pig)446
1521965-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
1522105-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
447717Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
554026Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466

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