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Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	XANOMELINE
Molecular formula	C14H23N3OS
IUPAC name	3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
Molecular weight	281.418
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.3
Synonyms	DTXSID60157286 LS-131633 Pyridine, 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl- 5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid ACMC-20aga8 C14H23N3OS Hexyloxy-TZTP LY-246708 SB18821 ZINC1532358 3-(4-(Hexyloxy)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methylpyridine AKOS016007489 D06330 KS-00000EZ0 NNC-11-0232 UNII-9ORI6L73CJ 3-(Hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole AC1L1TYQ C-33119 FT-0602214 Lumeron Pyridine,3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl- Xanomeline (USAN) 131986-45-3 5-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1-methyl-1,2,3,6-tetrahydropyridine AJ-26769 CC-20740 CHEMBL21536 JOLJIIDDOBNFHW-UHFFFAOYSA-N LY246708 SCHEMBL121046 3-(4-hexoxy-1,2,5-thiadiazol-3-yl)-1-methyl-5,6-dihydro-2H-pyridine ANW-72030 DS-15663 L000694 Pyridine, 3-(4-(hexyloxy)-1,2,5-thiadiazol-3-yl)-1,2,5,6-tetrahydro-1-methyl- VP14766 (3-O-hexyloxy)-TZTP 5-(4-HEXYLOXY-[1,2,5]THIADIAZOL-3-YL)-1-METHYL-1,2,3,6-TETRAHYDRO-PYRIDINE AC1Q4YKY C11767 CHEBI:10056 GTPL57 LY 246708 RT-024475 Xanomeline [USAN:INN] 3-(3-O-hexyl-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine 5-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1-methyl-1,2,3,6-tetrahydropyridine, AldrichCPR AK-57746 CTK4B7643 KB-233575 MolPort-023-334-334 ST24041615 3-(4-hexyloxy-1 ,2,5-thiadiazol-3-yl)-1 ,2,5,6-tetrahydro-1-methyl-pyridine 9ORI6L73CJ BDBM50003359 [ Show all ]
Inchi Key	JOLJIIDDOBNFHW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
PubChem CID	60809
ChEMBL	CHEMBL21536
IUPHAR	57
BindingDB	50003359
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
155995	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
156006	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
155989	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
155999	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
155998	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
156002	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
155993	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
155990	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
156000	5-hydroxytryptamine receptor 4	Q29006	HTR4	Sus scrofa (Pig)	137
156005	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
156004	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479
156001	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
155996	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
156007	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
155985	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
155991	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
156003	Muscarinic acetylcholine receptor M1	P12657	Chrm1	Mus musculus (Mouse)	460
155986	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
155997	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
155987	Muscarinic acetylcholine receptor M3	Q9ERZ3	Chrm3	Mus musculus (Mouse)	589