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Ligand

NameXANOMELINE
Molecular formulaC14H23N3OS
IUPAC name3-hexoxy-4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazole
Molecular weight281.418
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP3.3
Synonyms131986-45-3
3-(Hexyloxy)-4-(1-methyl-1,2,5,6-tetrahydropyridin-3-yl)-1,2,5-thiadiazole
LY 246708
LY-246708
Xanomeline [USAN:INN]
[ Show all ]
Inchi KeyJOLJIIDDOBNFHW-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H23N3OS/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12/h8H,3-7,9-11H2,1-2H3
PubChem CID60809
ChEMBLCHEMBL21536
IUPHAR57
BindingDB50003359
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 23
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
1559955-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1560065-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1559895-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1559995-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
1559985-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
1560025-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
1559935-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1559905-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1560005-hydroxytryptamine receptor 4Q29006HTR4Sus scrofa (Pig)137
1560055-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
1560045-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
156001Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
155996D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
156007D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
155985Muscarinic acetylcholine receptor M1P11229CHRM1Homo sapiens (Human)460
155991Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
156003Muscarinic acetylcholine receptor M1P12657Chrm1Mus musculus (Mouse)460
155986Muscarinic acetylcholine receptor M2P08172CHRM2Homo sapiens (Human)466
155997Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466
155987Muscarinic acetylcholine receptor M3Q9ERZ3Chrm3Mus musculus (Mouse)589

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