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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000516165
Molecular formula	C21H18N4O3S
IUPAC name	N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-6-oxo-1-phenyl-4,5-dihydropyridazine-3-carboxamide
Molecular weight	406.46
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.9
Synonyms	SMR000342434 HMS2656A03 AC1NCVLV N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-6-oxo-1-phenyl-4,5-dihydropyridazine-3-carboxamide CHEMBL1506308 BDBM54354 N-[4-(4-methoxyphenyl)-2-thiazolyl]-6-oxo-1-phenyl-4,5-dihydropyridazine-3-carboxamide cid_4540182 6-keto-N-[4-(4-methoxyphenyl)thiazol-2-yl]-1-phenyl-4,5-dihydropyridazine-3-carboxamide N-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-6-oxidanylidene-1-phenyl-4,5-dihydropyridazine-3-carboxamide [ Show all ]
Inchi Key	JQXROLXJEVWFRL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H18N4O3S/c1-28-16-9-7-14(8-10-16)18-13-29-21(22-18)23-20(27)17-11-12-19(26)25(24-17)15-5-3-2-4-6-15/h2-10,13H,11-12H2,1H3,(H,22,23,27)
PubChem CID	4540182
ChEMBL	CHEMBL1506308
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
157732	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
482394	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
157731	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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