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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Icomucret
Molecular formula	C20H32O3
IUPAC name	(5Z,8Z,11Z,13E,15S)-15-hydroxyicosa-5,8,11,13-tetraenoic acid
Molecular weight	320.473
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	5.1
Synonyms	BML1-B09 GTPL3401 IDI1_033807 SR-01000946930 (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosic acid (5Z,8Z,11Z,13E)-(15S)-15-Hydroxyicosa-5,8,11,13-tetraenoic acid 15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoate 44JHK6G39Q CHEBI:15558 HMS1989C19 NCGC00161242-01 ZINC4629861 (15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid (5Z,8Z,11Z,13E,15S)-15-hydroxyicosa-5,8,11,13-tetraenoic acid 15(S)-hydroxyeicosatetraenoic acid AL-12959 D08931 Icomucret (USAN) PROCALYX (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoate (15S,5Z,8Z,11Z,13E)-15-Hydroxyeicosatetraenoic acid 15 hete 15-Hydroxyeicosa-5,8,11,13-tetraenoic acid BSPBio_001337 HMS1361C19 LMFA03060001 SR-01000946930-1 (15S)-15-Hydroxy-5,8,11-cis-13-trans-icosatetraenoate (5Z,8Z,11Z,13E,15S)-15-hydroxy-5,8,11,13-eicosatetraenoic acid 15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid 54845-95-3 CHEMBL1907680 HMS3402C19 NCGC00161242-02 (15S)-hydroxyeicosa-(5Z,8Z,11Z,13E)-tetraenoic acid (S)-15-HETE 15(S)-hydroxyeicosatetraenoic acid (ophthalmic, dry eye), Alcon BDBM50421764 D0D6ZK Icomucret [USAN:INN] SCHEMBL994674 (15S)-15-Hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid (5Z,8Z,11Z,13E)-(15S)-15-Hydroxyicosa-5,8,11,13-tetraenoate 15(S)-HETE 15S-HETE C04742 HMS1791C19 MFCD00063590 UNII-44JHK6G39Q (15S)-15-Hydroxy-5,8,11-cis-13-trans-icosatetraenoic acid (5Z,8Z,11Z,13E,15S)-15-hydroxyeicosa-5,8,11,13-tetraenoic acid 15(S)-Hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoic acid, ~150 mug/mL in ethanol, >=97.0% (HPLC) AC1NQXHT CHEMBL594621 NCGC00161242-03 (15S,5Z,8Z,11Z,13E)-15-Hydroxyeicosatetraenoate 1224AH 15-Hete [ Show all ]
Inchi Key	JSFATNQSLKRBCI-VAEKSGALSA-N
Inchi ID	InChI=1S/C20H32O3/c1-2-3-13-16-19(21)17-14-11-9-7-5-4-6-8-10-12-15-18-20(22)23/h4-5,8-11,14,17,19,21H,2-3,6-7,12-13,15-16,18H2,1H3,(H,22,23)/b5-4-,10-8-,11-9-,17-14+/t19-/m0/s1
PubChem CID	5280724
ChEMBL	N/A
IUPHAR	3401
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554077	Leukotriene B4 receptor 2	Q9NPC1	LTB4R2	Homo sapiens (Human)	358

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