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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SKF 38393
Molecular formula	C16H17NO2
IUPAC name	5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Molecular weight	255.317
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	2.5
Synonyms	CCG-204528 GTPL935 NCGC00015299-04 R(+)SKF38393 SK-383933 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrochloride(SKF 38393) BDBM50004923 Lopac0_000436 NCGC00024875-02 SCHEMBL469578 SKF-38,393 1H-3-Benzazepine-7,8-diol,2,3,4,5-tetrahydro-1-phenyl-, hydrochloride (1:1) BRD-A88548664-001-02-3 BSPBio_002384 CTK5B5738 NCG-C00093856-01 PDSP1_001524 SK&F-383933 SKF38393(hydrochloride) 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol (SK&F 38393) 5-21-05-00258 (Beilstein Handbook Reference) API0009306 CHEBI:110200 KS-00001CZ8 NCGC00015299-05 R-SK&F 38393 (+/-)-SKF-38393 159795-65-0 6-PHENYL-4-AZOBICYCLO[5.4.0]UNDECA-7,9,11-TRIENE-9,10-DIOL Biomol-NT_000034 CHEMBL286080 LS-27997 NCGC00024875-03 SK&F 38393 SKF-38393 1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol 2,3,4,5-Tetrahydro-1-phenyl-1H-3-benzazepine-7,8-diol AC1L1B1H BRD-A88548664-004-01-9 C16H17NO2 D0OU7P NCGC00015299-03 PDSP2_001508 SK-38393 SPECTRUM1505101 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF 38393) 5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol BCP16347 CHEBI:131801 L000563 NCGC00015299-06 RS(+/-)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol SKF 38393-A (A+/-)-SKF-38393 hydrochloride 1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl- 67287-49-4 BPBio1_001229 BRN 1543419 cid_147514 MolPort-003-666-576 NCGC00024875-04 SK&F-38393 SKF38393 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine AC1Q79Q0 [ Show all ]
Inchi Key	JUDKOGFHZYMDMF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H17NO2/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11/h1-5,8-9,14,17-19H,6-7,10H2
PubChem CID	1242
ChEMBL	CHEMBL286080
IUPHAR	935
BindingDB	50004923
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
160035	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
556089	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
160039	Alpha-2C adrenergic receptor	P22086	Adra2c	Rattus norvegicus (Rat)	458
482677	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
160031	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
160033	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
160038	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
160032	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
160040	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
160034	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
160036	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
160037	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
160041	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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