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Ligand

NameMGS-0028
Molecular formulaC8H8FNO5
IUPAC name(1R,2S,5S,6S)-2-amino-6-fluoro-4-oxobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight217.152
Hydrogen bond acceptor7
Hydrogen bond donor3
XlogP-4.2
Synonyms(+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
(+)-MGS-0028
(+/-)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
(-)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
(1r,2s,5s,6s)-2-amino-6-fluoro-4-oxobicyclo[3.1.0]hexane 2,6-dicarboxylic acid
[ Show all ]
Inchi KeyKFAGJPNFERWZJA-JKBXLQNXSA-N
Inchi IDInChI=1S/C8H8FNO5/c9-8(6(14)15)3-2(11)1-7(10,4(3)8)5(12)13/h3-4H,1,10H2,(H,12,13)(H,14,15)/t3-,4-,7+,8-/m1/s1
PubChem CID9837317
ChEMBLCHEMBL121053
IUPHAR1395
BindingDB50094843
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
167548Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
167545Metabotropic glutamate receptor 2P31421Grm2Rattus norvegicus (Rat)872
167550Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
167546Metabotropic glutamate receptor 3Q14832GRM3Homo sapiens (Human)879
167549Metabotropic glutamate receptor 3P31422Grm3Rattus norvegicus (Rat)879
167552Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
167551Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212
167547Metabotropic glutamate receptor 6O15303GRM6Homo sapiens (Human)877
167553Metabotropic glutamate receptor 7Q14831GRM7Homo sapiens (Human)915

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