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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000147498
Molecular formula	C22H20ClN3OS2
IUPAC name	3-amino-4-(4-chlorophenyl)-N,N-diethyl-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide
Molecular weight	441.992
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.2
Synonyms	AC1LR0KQ MolPort-000-701-624 CHEMBL1488995 STK546025 3-amino-4-(4-chlorophenyl)-N,N-diethyl-6-thiophen-2-ylthieno[2,3-b]pyridine-2-carboxamide MCULE-6617781972 AKOS003680476 RSC005370 EU-0081186 ZINC1295962 3-Amino-4-(4-chloro-phenyl)-6-thiophen-2-yl-thieno[2,3-b]pyridine-2-carboxylic acid diethylamide 499119-74-3 MLS000555981 HMS2348B21 3-amino-4-(4-chlorophenyl)-N,N-diethyl-6-(thiophen-2-yl)thieno[2,3-b]pyridine-2-carboxamide [ Show all ]
Inchi Key	KGKFCPHSLHZTNV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H20ClN3OS2/c1-3-26(4-2)22(27)20-19(24)18-15(13-7-9-14(23)10-8-13)12-16(25-21(18)29-20)17-6-5-11-28-17/h5-12H,3-4,24H2,1-2H3
PubChem CID	1415522
ChEMBL	CHEMBL1488995
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
168569	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
168571	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
168570	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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