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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL10309
Molecular formula	C23H25BrN2O2
IUPAC name	3-[1-[(4-bromophenyl)methyl]piperidin-4-yl]-3-phenylpiperidine-2,6-dione
Molecular weight	441.369
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.8
Synonyms	1''-(4-Bromo-benzyl)-3-phenyl-[3,4'']bipiperidinyl-2,6-dione (+/-)-1''-(4-bromobenzyl)-3-phenyl-3,4''-bipiperidine-2,6-dione (-)-1''-(4-bromobenzyl)-3-phenyl-3,4''-bipiperidine-2,6-dione BDBM50018553 (+)-1''-(4-bromobenzyl)-3-phenyl-3,4''-bipiperidine-2,6-dione SCHEMBL13962970 [ Show all ]
Inchi Key	KIBLABCMQPRMIQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25BrN2O2/c24-20-8-6-17(7-9-20)16-26-14-11-19(12-15-26)23(18-4-2-1-3-5-18)13-10-21(27)25-22(23)28/h1-9,19H,10-16H2,(H,25,27,28)
PubChem CID	14479864
ChEMBL	CHEMBL10309
IUPHAR	N/A
BindingDB	50018553
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
169680	C-C chemokine receptor type 1	P32246	CCR1	Homo sapiens (Human)	355
169678	C-C chemokine receptor type 2	P41597	CCR2	Homo sapiens (Human)	374
169683	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
169679	C-X-C chemokine receptor type 3	P49682	CXCR3	Homo sapiens (Human)	368
169685	CX3C chemokine receptor 1	P49238	CX3CR1	Homo sapiens (Human)	355
169682	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
169681	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
169677	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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