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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL371031
Molecular formula	C29H28ClF3N2O
IUPAC name	5-[4-[4-chloro-3-(trifluoromethyl)phenyl]-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile
Molecular weight	513.001
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	6.5
Synonyms	BDBM50027209 SCHEMBL904956 5-[4-(4-Chloro-3-trifluoromethyl-phenyl)-4-hydroxy-piperidin-1-yl]-2,2-diphenyl-pentanenitrile
Inchi Key	KJWMVKZBUSNLLL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H28ClF3N2O/c30-26-13-12-24(20-25(26)29(31,32)33)28(36)15-18-35(19-16-28)17-7-14-27(21-34,22-8-3-1-4-9-22)23-10-5-2-6-11-23/h1-6,8-13,20,36H,7,14-19H2
PubChem CID	11584791
ChEMBL	CHEMBL371031
IUPHAR	N/A
BindingDB	50027209
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
170890	G-protein coupled receptor homolog US28	P69332	US28	Human cytomegalovirus (strain AD169) (HHV-5)	354

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