Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE WDL-RF ATPbind DockRMSD DeepMSA FASPR

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

Ligand

Name15532-75-9
Molecular formulaC11H13F3N2
IUPAC name1-[3-(trifluoromethyl)phenyl]piperazine
Molecular weight230.234
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP2.3
Synonyms1-[3-(Trifluoromethyl)phenyl]piperazine
1-(3-(Trifluoromethyl)phenyl)piperazine
TFMPP
1-(3-Trifluoromethylphenyl)piperazine
N-(3-trifluoromethylphenyl)piperazine
[ Show all ]
Inchi KeyKKIMDKMETPPURN-UHFFFAOYSA-N
Inchi IDInChI=1S/C11H13F3N2/c12-11(13,14)9-2-1-3-10(8-9)16-6-4-15-5-7-16/h1-3,8,15H,4-7H2
PubChem CID4296
ChEMBLCHEMBL274866
IUPHAR115
BindingDB50007406
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Total entries: 24
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
1711655-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1711665-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1711685-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
1711675-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1711745-hydroxytryptamine receptor 1DP11614HTR1DCanis lupus familiaris (Dog)377
1711815-hydroxytryptamine receptor 1DP28565Htr1dRattus norvegicus (Rat)374
1711705-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
1711775-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
1711825-hydroxytryptamine receptor 1FQ02284Htr1fMus musculus (Mouse)366
1711715-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5561515-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1711625-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1711635-hydroxytryptamine receptor 2BP30994Htr2bRattus norvegicus (Rat)479
1711605-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1711695-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
1711725-hydroxytryptamine receptor 5AP30966Htr5aMus musculus (Mouse)357
1711755-hydroxytryptamine receptor 5BP31387Htr5bMus musculus (Mouse)370
1711615-hydroxytryptamine receptor 6Q9R1C8Htr6Mus musculus (Mouse)440
1711645-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
1711735-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218