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Ligand

Namethioridazine
Molecular formulaC21H26N2S2
IUPAC name10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
Molecular weight370.573
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP5.9
SynonymsMellaril
Thioridazin
Melleril
Meleril
50-52-2
[ Show all ]
Inchi KeyKLBQZWRITKRQQV-UHFFFAOYSA-N
Inchi IDInChI=1S/C21H26N2S2/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3
PubChem CID5452
ChEMBLCHEMBL479
IUPHAR100
BindingDB50002338
DrugBankDB00679

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 56
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
1717715-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1717915-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1718105-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1718015-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1717975-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
1717635-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5561525-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1718065-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1717755-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1717835-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
1718055-hydroxytryptamine receptor 5AP47898HTR5AHomo sapiens (Human)357
1717655-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
1717785-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
1717745-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
5541485-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
171768Adenosine receptor A1P25099Adora1Rattus norvegicus (Rat)326
171796Alpha-1A adrenergic receptorQ9WU25ADRA1ACavia porcellus (Guinea pig)466
171803Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
171813Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
171784Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520

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