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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Methysergidum
Molecular formula	C21H27N3O2
IUPAC name	(6aR,9R)-N-(1-hydroxybutan-2-yl)-4,7-dimethyl-6,6a,8,9-tetrahydroindolo[4,3-fg]quinoline-9-carboxamide
Molecular weight	353.466
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.3
Synonyms	(8R)-N-[1-hydroxymethyl(propyl)]-1,6-dimethyl-9,10-didehydroergoline-8-carboxamide 1-Methyllysergic acid butanolamide metisergida CHEBI:584020 (?)-9,10-Didehydro-N-[1-(hydroxymethyl)propyl]-1,6-dimethylergoline-8beta-carboxamide DB00247 191039-EP2275420A1 N-(1-(Hydroxymethyl)propyl)-1-methyl-dextro-(+)-lysergamide CHEMBL485253 1-Methyl-D-lysergic acid butanolamide 191039-EP2280008A2 SCHEMBL467883 [ Show all ]
Inchi Key	KPJZHOPZRAFDTN-NQUBZZJWSA-N
Inchi ID	InChI=1S/C21H27N3O2/c1-4-15(12-25)22-21(26)14-8-17-16-6-5-7-18-20(16)13(10-23(18)2)9-19(17)24(3)11-14/h5-8,10,14-15,19,25H,4,9,11-12H2,1-3H3,(H,22,26)/t14-,15?,19-/m1/s1
PubChem CID	6540428
ChEMBL	N/A
IUPHAR	N/A
BindingDB	N/A
DrugBank	DB00247
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
174823	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
174818	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
174821	5-hydroxytryptamine receptor 1E	P28566	HTR1E	Homo sapiens (Human)	365
174817	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366
174824	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
174820	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
174822	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
174819	5-hydroxytryptamine receptor 7	P34969	HTR7	Homo sapiens (Human)	479

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