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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL304919
Molecular formula	C20H22N2O4
IUPAC name	(2R,4R)-4-amino-1-(2,2-diphenylethyl)pyrrolidine-2,4-dicarboxylic acid
Molecular weight	354.406
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-2.6
Synonyms	BDBM50071151 SCHEMBL8972526 (2R,4R)-4-Amino-1-(2,2-diphenyl-ethyl)-pyrrolidine-2,4-dicarboxylic acid
Inchi Key	KWABXRJYGGENTG-YLJYHZDGSA-N
Inchi ID	InChI=1S/C20H22N2O4/c21-20(19(25)26)11-17(18(23)24)22(13-20)12-16(14-7-3-1-4-8-14)15-9-5-2-6-10-15/h1-10,16-17H,11-13,21H2,(H,23,24)(H,25,26)/t17-,20-/m1/s1
PubChem CID	44302856
ChEMBL	CHEMBL304919
IUPHAR	N/A
BindingDB	50071151
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
179637	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
179641	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
179639	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
179640	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
179642	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
179638	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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