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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL61861
Molecular formula	C19H19F3NO3-
IUPAC name	2-[methyl-[(3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propyl]amino]acetate
Molecular weight	366.36
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	2.5
Synonyms	NCGC00162043-03 NCGC00162043-01 ORG-24598 BDBM50421506 NCGC00162043-02
Inchi Key	KZWQAWBTWNPFPW-QGZVFWFLSA-M
Inchi ID	InChI=1S/C19H20F3NO3/c1-23(13-18(24)25)12-11-17(14-5-3-2-4-6-14)26-16-9-7-15(8-10-16)19(20,21)22/h2-10,17H,11-13H2,1H3,(H,24,25)/p-1/t17-/m1/s1
PubChem CID	16759590
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50421506
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
563061	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
563067	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
563056	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
563064	5-hydroxytryptamine receptor 6	P31388	Htr6	Rattus norvegicus (Rat)	436
563063	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
563057	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
563060	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
563062	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
563059	Beta-1 adrenergic receptor	P08588	ADRB1	Homo sapiens (Human)	477
563058	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
563066	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
563065	D(4) dopamine receptor	P30729	Drd4	Rattus norvegicus (Rat)	387

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