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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL140197
Molecular formula	C6H9NO5
IUPAC name	(1R,2S,3R)-2-[(S)-amino(carboxy)methyl]-3-hydroxycyclopropane-1-carboxylic acid
Molecular weight	175.14
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-3.9
Synonyms	BDBM50138784 (1R,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-hydroxy-cyclopropanecarboxylic acid
Inchi Key	LGSORWLWDBCUMM-NTAGLIMJSA-N
Inchi ID	InChI=1S/C6H9NO5/c7-3(6(11)12)1-2(4(1)8)5(9)10/h1-4,8H,7H2,(H,9,10)(H,11,12)/t1-,2+,3-,4+/m0/s1
PubChem CID	44361401
ChEMBL	CHEMBL140197
IUPHAR	N/A
BindingDB	50138784
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
187017	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
187012	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
187020	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
187015	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
187018	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
187021	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
187016	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
187019	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
187013	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
187014	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

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