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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	BDBM85398
Molecular formula	C28H32BrFN4
IUPAC name	N-[2-bromo-4-(2-methylpropyl)phenyl]-N-ethyl-4-[5-(3-fluorophenyl)-3,6-dihydro-2H-pyridin-1-yl]-6-methylpyrimidin-2-amine
Molecular weight	523.494
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	7.7
Synonyms	CRA1001
Inchi Key	LHHWPOJOJLAJFX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H32BrFN4/c1-5-34(26-12-11-21(14-19(2)3)16-25(26)29)28-31-20(4)15-27(32-28)33-13-7-9-23(18-33)22-8-6-10-24(30)17-22/h6,8-12,15-17,19H,5,7,13-14,18H2,1-4H3
PubChem CID	57340110
ChEMBL	N/A
IUPHAR	N/A
BindingDB	85398
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
187540	Corticotropin-releasing factor receptor 1	P35353	Crhr1	Rattus norvegicus (Rat)	415
556227	Corticotropin-releasing factor receptor 2	P47866	Crhr2	Rattus norvegicus (Rat)	411

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