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Ligand

NameCHEMBL2373733
Molecular formulaC21H16ClN3O3
IUPAC nameN-[3-chloro-4-[(1S,2R,6R,7R)-3,5-dioxo-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl]phenyl]pyridine-2-carboxamide
Molecular weight393.827
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP2.6
SynonymsN/A
Inchi KeyLJUABYFUJVRUSJ-FVEFGIFQSA-N
Inchi IDInChI=1S/C21H16ClN3O3/c22-14-10-13(24-19(26)15-3-1-2-8-23-15)6-7-16(14)25-20(27)17-11-4-5-12(9-11)18(17)21(25)28/h1-8,10-12,17-18H,9H2,(H,24,26)/t11-,12+,17-,18-/m1/s1
PubChem CID90661779
ChEMBLCHEMBL2373733
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
189232Metabotropic glutamate receptor 1P23385Grm1Rattus norvegicus (Rat)1199
189235Metabotropic glutamate receptor 2P31421Grm2Rattus norvegicus (Rat)872
189230Metabotropic glutamate receptor 3P31422Grm3Rattus norvegicus (Rat)879
189228Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
189229Metabotropic glutamate receptor 4P31423Grm4Rattus norvegicus (Rat)912
189231Metabotropic glutamate receptor 5P31424Grm5Rattus norvegicus (Rat)1203
189234Metabotropic glutamate receptor 6O15303GRM6Homo sapiens (Human)877
189233Metabotropic glutamate receptor 7P35400Grm7Rattus norvegicus (Rat)915
189227Metabotropic glutamate receptor 8P70579Grm8Rattus norvegicus (Rat)908

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