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Ligand

NameL-741,626
Molecular formulaC20H21ClN2O
IUPAC name4-(4-chlorophenyl)-1-(1H-indol-3-ylmethyl)piperidin-4-ol
Molecular weight340.851
Hydrogen bond acceptor2
Hydrogen bond donor2
XlogP3.7
Synonyms81226-60-0
L-741626
3-(4-(4-Chlorophenyl-4-hydroxypiperidino)methyl)indole
L 741626
L 741,626
[ Show all ]
Inchi KeyLLBLNMUONVVVPG-UHFFFAOYSA-N
Inchi IDInChI=1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2
PubChem CID133633
ChEMBLCHEMBL445102
IUPHAR177
BindingDB50050467
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 19
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1900955-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1900975-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1900875-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1900965-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1900885-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5562365-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1900815-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1900915-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
190093Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
190090Alpha-2A adrenergic receptorP22909Adra2aRattus norvegicus (Rat)450
190085D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
190083D(1B) dopamine receptorP21918DRD5Homo sapiens (Human)477
190086D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
556235D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
190084D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
190082D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467
190092Glucagon-like peptide 1 receptorP43220GLP1RHomo sapiens (Human)463
190089Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
190094Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

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