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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1098211
Molecular formula	C17H12N2O
IUPAC name	2-hydroxy-5-(2-methylquinolin-7-yl)benzonitrile
Molecular weight	260.296
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM50317842 2-Hydroxy-5-(2-methylquinolin-7-yl)benzonitrile
Inchi Key	LUNGUUZUIGBWQL-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H12N2O/c1-11-2-3-12-4-5-14(9-16(12)19-11)13-6-7-17(20)15(8-13)10-18/h2-9,20H,1H3
PubChem CID	136086761
ChEMBL	CHEMBL1098211
IUPHAR	N/A
BindingDB	50317842
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
563498	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
563496	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
563500	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
563495	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
563497	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
563499	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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