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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL356912
Molecular formula	C27H29ClN2
IUPAC name	(2R,3R)-2-benzhydryl-N-[(2-chlorophenyl)methyl]-1-azabicyclo[2.2.2]octan-3-amine
Molecular weight	416.993
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	6.0
Synonyms	(2-Chloro-benzyl)-[(2R,3R)-2-(2,2-diphenyl-ethyl)-1-aza-bicyclo[2.2.2]oct-3-yl]-amine BDBM50280458 2alpha-(Diphenylmethyl)-N-(2-chlorobenzyl)quinuclidin-3alpha-amine
Inchi Key	LURXNRSWKKLLDE-KAYWLYCHSA-N
Inchi ID	InChI=1S/C27H29ClN2/c28-24-14-8-7-13-23(24)19-29-26-22-15-17-30(18-16-22)27(26)25(20-9-3-1-4-10-20)21-11-5-2-6-12-21/h1-14,22,25-27,29H,15-19H2/t26-,27-/m1/s1
PubChem CID	10202046
ChEMBL	CHEMBL356912
IUPHAR	N/A
BindingDB	50280458
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
196880	Neuromedin-K receptor	P16177	Tacr3	Rattus norvegicus (Rat)	452
196878	Substance-K receptor	P51144	TACR2	Mesocricetus auratus (Golden hamster)	384
196879	Substance-P receptor	P14600	Tacr1	Rattus norvegicus (Rat)	407
196881	Substance-P receptor	P30547	TACR1	Cavia porcellus (Guinea pig)	407

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