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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1,3-Diethyl-8-phenylxanthine
Molecular formula	C15H16N4O2
IUPAC name	1,3-diethyl-8-phenyl-7H-purine-2,6-dione
Molecular weight	284.319
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.9
Synonyms	DEPX NCGC00014999-02 PDSP2_000975 1,3-Diethyl-8-phenyl-3,7-dihydro-purine-2,6-dione 75922-48-4 C-48797 GTPL445 PDSP1_000323 SR-01000075182-1 1,3-Dithyl-8-phenylxanthine AC1L1B8H D07HKU Lopac0_000125 PDSP2_000321 1,3-Diethyl-3,9-dihydro-8-phenyl-1H-purine-2,6-dione 2KCV39GKGL AKOS027378654 EU-0100125 NCGC00093616-01 SCHEMBL1321894 1,3-diethyl-8-phenyl-7H-purine-2,6-dione 8-Phenyl-1,3-diethylxanthine CAS_1328 CHEMBL11348 L001207 PDSP1_000326 UNII-2KCV39GKGL 1H-Purine-2,6-dione, 1,3-diethyl-3,7-dihydro-8-phenyl- AC1Q312F D0BD8N NCGC00014999-01 PDSP2_000324 1,3-Diethyl-8-phenyl-1H-purine-2,6(3H,7H)-dione BDBM81971 FT-0606658 NSC_1328 SR-01000075182 CCG-204220 CTK5E2202 Lopac-A-003 PDSP1_000991 ZINC9229229 1H-Purine-2,6-dione,1,3-diethyl-3,9-dihydro-8-phenyl- AC1Q6LCB [ Show all ]
Inchi Key	LVSWNSHUTPWCNF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H16N4O2/c1-3-18-13-11(14(20)19(4-2)15(18)21)16-12(17-13)10-8-6-5-7-9-10/h5-9H,3-4H2,1-2H3,(H,16,17)
PubChem CID	1328
ChEMBL	CHEMBL11348
IUPHAR	445
BindingDB	81971
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
197599	Adenosine receptor A1	P49892	ADORA1	Gallus gallus (Chicken)	324
197600	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
197601	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
556264	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
197597	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
197598	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
197602	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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