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Ligand

Namealpha-methyl-5-HT
Molecular formulaC11H14N2O
IUPAC name3-(2-aminopropyl)-1H-indol-5-ol
Molecular weight190.246
Hydrogen bond acceptor2
Hydrogen bond donor3
XlogP0.6
Synonymsalpha-Methylserotonin
3-(2-aminopropyl)-1H-indol-5-ol
alpha-Me-5-HT
CHEMBL275854
CHEBI:48295
[ Show all ]
Inchi KeyLYPCGXKCQDYTFV-UHFFFAOYSA-N
Inchi IDInChI=1S/C11H14N2O/c1-7(12)4-8-6-13-11-3-2-9(14)5-10(8)11/h2-3,5-7,13-14H,4,12H2,1H3
PubChem CID2107
ChEMBLCHEMBL275854
IUPHAR152
BindingDB50014945
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 18
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1995705-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
1995835-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
1995815-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
1995845-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
1995685-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
1995795-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
1995755-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
1995745-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
1995775-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
1995675-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
1995715-hydroxytryptamine receptor 2BP30994Htr2bRattus norvegicus (Rat)479
1995725-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
1995735-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
1995765-hydroxytryptamine receptor 4O70528HTR4Cavia porcellus (Guinea pig)388
5542925-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
5542935-hydroxytryptamine receptor 4Q62758Htr4Rattus norvegicus (Rat)406
5542915-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
199582D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446

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