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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	159277-08-4
Molecular formula	C11H14F3NO2
IUPAC name	2-[2,5-dimethoxy-4-(trifluoromethyl)phenyl]ethanamine
Molecular weight	249.233
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.1
Synonyms	Benzeneethanamine, 2,5-dimethoxy-4-(trifluoromethyl)- 2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-ethylamine DTXSID70439308 4-Trifluoromethyl-2,5-dimethoxybenzeneethanamine AKOS022182192 ZINC13739909 2,5-DIMETHOXY-4-(TRIFLUOROMETHYL)PHENETHYLAMINE 2-[2,5-Dimethoxy-4-(trifluoromethyl)phenyl]ethan-1-amine SCHEMBL14655561 16O4G6IKYL BDBM50038369 2-(2,5-dimethoxy-4-(trifluoromethyl)phenyl)ethanamine CHEMBL136354 2C-TFM AJ-64353 UNII-16O4G6IKYL 2,5-Dimethoxy-4-(trifluoromethyl)-benzeneethanamine [ Show all ]
Inchi Key	LYXGNMLWYONZID-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H14F3NO2/c1-16-9-6-8(11(12,13)14)10(17-2)5-7(9)3-4-15/h5-6H,3-4,15H2,1-2H3
PubChem CID	10399795
ChEMBL	CHEMBL136354
IUPHAR	N/A
BindingDB	50038369
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
199763	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
199762	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
199761	5-hydroxytryptamine receptor 2C	P34968	Htr2c	Mus musculus (Mouse)	459

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