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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL477008
Molecular formula	C29H29N5O2
IUPAC name	N-[2-methyl-3-[(6-oxo-4-piperazin-1-ylpyridazin-1-yl)methyl]phenyl]-4-phenylbenzamide
Molecular weight	479.584
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM50412988
Inchi Key	MAQUYJAFLAKYAE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H29N5O2/c1-21-25(20-34-28(35)18-26(19-31-34)33-16-14-30-15-17-33)8-5-9-27(21)32-29(36)24-12-10-23(11-13-24)22-6-3-2-4-7-22/h2-13,18-19,30H,14-17,20H2,1H3,(H,32,36)
PubChem CID	25209050
ChEMBL	CHEMBL477008
IUPHAR	N/A
BindingDB	50412988
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
200941	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
200939	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
200940	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
200942	Mas-related G-protein coupled receptor member X1	Q96LB2	MRGPRX1	Homo sapiens (Human)	322

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