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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LY334370
Molecular formula	C21H22FN3O
IUPAC name	4-fluoro-N-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]benzamide
Molecular weight	351.425
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	3.6
Synonyms	L000364 ZINC1488294 4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indol-5-yl]-benzamide D09GHO LY-334370 182563-08-2 5Q7I1WL2UY BDBM50130461 GTPL20 SCHEMBL6911508 4-fluoro-N-[3-(1-methyl-4-piperidinyl)-1h-indol-5-yl]-benzamide CHEMBL101690 LY 334370 [3H]LY334370 4-fluoro-N-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]benzamide DTXSID40415518 AC1NSKBH Benzamide, 4-fluoro-N-(3-(1-methyl-4-piperidinyl)-1H-indol-5-yl)- HY-103107 UNII-5Q7I1WL2UY 4-fluoro-n-[3-(1-methyl-4-piperidinyl)-1h-indol-5-yl]benzamide CS-0025021 LY-334,370 BCP29131 GTPL151 NCGC00378776-02 4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benzamide [ Show all ]
Inchi Key	MDMJLMDBRQXOOI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H22FN3O/c1-25-10-8-14(9-11-25)19-13-23-20-7-6-17(12-18(19)20)24-21(26)15-2-4-16(22)5-3-15/h2-7,12-14,23H,8-11H2,1H3,(H,24,26)
PubChem CID	5311258
ChEMBL	CHEMBL101690
IUPHAR	20, 151
BindingDB	50130461
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
202804	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
202807	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
202805	5-hydroxytryptamine receptor 1D	P28221	HTR1D	Homo sapiens (Human)	377
202806	5-hydroxytryptamine receptor 1F	P30939	HTR1F	Homo sapiens (Human)	366

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