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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1922022
Molecular formula	C26H27FN8O2
IUPAC name	4-N-(3-fluoro-4-methoxyphenyl)-2-N-(4-methoxyphenyl)-6-(4-pyrimidin-2-ylpiperazin-1-yl)pyrimidine-2,4-diamine
Molecular weight	502.554
Hydrogen bond acceptor	11
Hydrogen bond donor	2
XlogP	4.7
Synonyms	BDBM50358670 SCHEMBL10143488
Inchi Key	MGOYDGQTNJPALW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27FN8O2/c1-36-20-7-4-18(5-8-20)31-25-32-23(30-19-6-9-22(37-2)21(27)16-19)17-24(33-25)34-12-14-35(15-13-34)26-28-10-3-11-29-26/h3-11,16-17H,12-15H2,1-2H3,(H2,30,31,32,33)
PubChem CID	57395996
ChEMBL	CHEMBL1922022
IUPHAR	N/A
BindingDB	50358670
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
204891	Galanin receptor type 1	P47211	GALR1	Homo sapiens (Human)	349
204890	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387

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