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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2207643
Molecular formula	C22H24N2O
IUPAC name	1-(azulen-1-ylmethyl)-4-(2-methoxyphenyl)piperazine
Molecular weight	332.447
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.3
Synonyms	1-(1-azulenylmethyl)-4-(2-methoxyphenyl)piperazine 387360-48-7 KB-272557 AKOS024327376 ST50451974 1-(azulen-1-ylmethyl)-4-(2-methoxyphenyl)piperazine MCULE-8261633067 BDBM50401953 ZINC54960009 1-[4-(azulenylmethyl)piperazinyl]-2-methoxybenzene fauc-3019 AC1MVZR6 SBB056630 [ Show all ]
Inchi Key	MNVDCQLMHFFYCU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H24N2O/c1-25-22-10-6-5-9-21(22)24-15-13-23(14-16-24)17-19-12-11-18-7-3-2-4-8-20(18)19/h2-12H,13-17H2,1H3
PubChem CID	3716121
ChEMBL	CHEMBL2207643
IUPHAR	N/A
BindingDB	50401953
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
210104	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
210107	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
210106	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
210105	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
527546	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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