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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Linifanib
Molecular formula	C21H18FN5O
IUPAC name	1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea
Molecular weight	375.407
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	3.9
Synonyms	PC402063 S06-0034 4CA-0745 UNII-CO93X137CW ABT-869,Linifanib AL-39324 BCP9000220 CS-0115 HMS3244D06 Kinome_532 MLS006010276 QCR-97 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea SC-87820 AB1008464 X7465 AC-24279 AN-503 BRD-K99749624-001-01-3 D0M9QZ HMS3654E03 Linifanib (ABT-869) N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)urea NCGC00250403-01 RS0095 SW218116-2 ABT-869 AKOS015919098 BC640336 cid_11485656 FT-0670795 JSPY-st000257 Linifanib [USAN:INN] PubChem22400 s1003 796967-16-3 Urea, N-(4-(3-amino-1H-indazol-4-yl)phenyl)-N'-(2-fluoro-5-methylphenyl)- ABT869 AL39324 BCPP000446 CTK8F0042 HMS3244D10 KS-00000I9Z MolPort-009-679-408 RG-3635 1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea SCHEMBL93804 ABP000856 ZINC6718813 AJ-56734 AOB87120 CHEBI:91435 DTXSID40229834 HY-50751 Linifanib (USAN/INN) N-(4-(3-Amino-1H-indazol-4-yl)phenyl)-N1-(2-fluoro-5-methylphenyl)urea PB34634 RT-011155 3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea SYN1002 ABT-869(Linifanib)/AL-39324,RG3635/ AL 39324 BCP01726 CO93X137CW GTPL5657 KB-08836 linifanibum Q-2136 1-(4-(3-amino-1H-indazol-4-yl)phenyl)-3-(2-fluoro-5-methylphenyl)urea S1003_Selleck AB0008062 VZ31170 ABT869, Linifanib, AL-39324, RG3635 Aminoindazole, 3 BDBM21079 D09635 HMS3244D14 MPVGZUGXCQEXTM-UHFFFAOYSA-N RG3635 1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluoranyl-5-methyl-phenyl)urea SMR004701346 ABT 869 AK-40846 AS-16177 CHEMBL223360 EX-A014 J-503186 Linifanib - ABT-869 N-[4-(3-amino-1H-indazol-4-yl)phenyl]-N'-(2-fluoro-5-methylphenyl)urea [ Show all ]
Inchi Key	MPVGZUGXCQEXTM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)
PubChem CID	11485656
ChEMBL	N/A
IUPHAR	N/A
BindingDB	21079
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
461065	P2Y purinoceptor 14	Q15391	P2RY14	Homo sapiens (Human)	338

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