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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17418721
Molecular formula	C33H39FN2O6
IUPAC name	(3S)-3-cyclopropyl-3-[3-[[5-(2-fluoro-5-methoxyphenyl)-6-(2,2,6,6-tetramethyloxan-4-yl)oxypyrazin-2-yl]methoxy]phenyl]propanoic acid
Molecular weight	578.681
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	5.6
Synonyms	BDBM168165 US9688642, 26 (3S)-3-Cyclopropyl-3-(3-((5-(2-fluoro-5-methoxyphenyl)-6-(2,2,6,6-tetramethyl-tetrahydro-2H-pyran-4-yloxy)pyrazin-2-yl)methoxy)phenyl)propanoic acid MRBDSBIVJCROCF-SANMLTNESA-N
Inchi Key	MRBDSBIVJCROCF-SANMLTNESA-N
Inchi ID	InChI=1S/C33H39FN2O6/c1-32(2)16-25(17-33(3,4)42-32)41-31-30(27-14-23(39-5)11-12-28(27)34)35-18-22(36-31)19-40-24-8-6-7-21(13-24)26(15-29(37)38)20-9-10-20/h6-8,11-14,18,20,25-26H,9-10,15-17,19H2,1-5H3,(H,37,38)/t26-/m0/s1
PubChem CID	118645505
ChEMBL	N/A
IUPHAR	N/A
BindingDB	168165
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
564007	Free fatty acid receptor 1	O14842	FFAR1	Homo sapiens (Human)	300
564008	Free fatty acid receptor 1	Q8K3T4	Ffar1	Rattus norvegicus (Rat)	300

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