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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1271476
Molecular formula	C21H20ClN3O2
IUPAC name	1-[1-[(2-chlorophenyl)methyl]-2-oxopyridin-3-yl]-3-(3-ethylphenyl)urea
Molecular weight	381.86
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	4.1
Synonyms	BDBM50417192
Inchi Key	MYTRTEZPNKENOK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H20ClN3O2/c1-2-15-7-5-9-17(13-15)23-21(27)24-19-11-6-12-25(20(19)26)14-16-8-3-4-10-18(16)22/h3-13H,2,14H2,1H3,(H2,23,24,27)
PubChem CID	52946883
ChEMBL	CHEMBL1271476
IUPHAR	N/A
BindingDB	50417192
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
217447	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
217449	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
217452	Prostaglandin E2 receptor EP3 subtype	P34980	Ptger3	Rattus norvegicus (Rat)	365
217453	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
217448	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
217451	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
217450	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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