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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Pranlukast
Molecular formula	C27H23N5O4
IUPAC name	N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide
Molecular weight	481.512
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	4.2
Synonyms	SR-05000001474-3 API0009100 BRD-K97045029-001-04-3 CTK7F7297 DTXSID3043782 K-0349 MolPort-035-394-920 N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenylbutoxy)benzamide Ono-RS-411 103177-37-3 (anhyd.) SB19080 8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5-yl)-4-oxo-4H-1-benzopyran AC-696 UNII-TB8Z891092 Azlaire (TN) CCN 00401 GTPL3634 LS-194954 N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4(4-phenylbutoxy)benzamide NBQKINXMPLXUET-UHFFFAOYSA-N SCHEMBL3693 SR-05000001474-1 AKOS015967342 BDBM50023198 CHEMBL21333 DSSTox_GSID_43782 HMS3714E03 MLS006010078 N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenyl-butoxy)-benzamide (ONO-RS-411) ONO RS-411 Pranlukast [INN:BAN] 8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran AB01275471-01 TB8Z891092 AS-15105 CAS-103177-37-3 D08408 FT-0652673 KS-00000YQJ N-(4-OXO-2-(1H-TETRAZOL-5-YL)-4H-CHROMEN-8-YL)-4-(4-PHENYLBUTOXY)BENZAMIDE N-[4-oxo-2-(2H-tetrazol-5-yl)-1-benzopyran-8-yl]-4-(4-phenylbutoxy)benzamide Onon 150821-03-7 SC-15917 AC1L1J6B ZINC1542146 BC220515 CHEBI:94810 DB01411 HMS2089H16 LS-194966 N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-P-(4-phenylbutoxy)benzamide;N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-P-(4-phenylbutoxy)benzamide NCGC00181765-01 Pranlukast (INN) 4-Oxo-8-(4-(4-phenylbutoxy)benzoylamino)-2-(tetrazol-5-yl)-4H-1-benzopyran SMR004701229 SR-05000001474-2 AN-15615 BRD-K97045029-001-01-9 CS-2304 DSSTox_RID_80074 HY-B0290 MolPort-003-849-959 N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenyl-butoxy)-benzamide(ONO-RS-411) Ono-1078 103177-37-3 SB-205312 8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran;8-[4(4-phenylbutoxy)benzoyl]amino-2-(5-tetrazolyl)-4-oxo-4H-1-benzopyran AB2000316 Tox21_112952 Azlaire CCG-220661 D08QIP GP8160 L013134 N-(4-oxo-2-(2H-tetrazol-5-yl)-4H-chromen-8-yl)-4-(4-phenylbutoxy)benzamide N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide P2115 177P373 SCHEMBL18058592 SR-05000001474 AK481332 BCP04577 DSSTox_CID_23782 HMS3650A14 MFCD24539454 N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenyl-butoxy)-benzamide O046 pranlukast hydrate [ Show all ]
Inchi Key	NBQKINXMPLXUET-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H23N5O4/c33-23-17-24(26-29-31-32-30-26)36-25-21(23)10-6-11-22(25)28-27(34)19-12-14-20(15-13-19)35-16-5-4-9-18-7-2-1-3-8-18/h1-3,6-8,10-15,17H,4-5,9,16H2,(H,28,34)(H,29,30,31,32)
PubChem CID	4887
ChEMBL	CHEMBL21333
IUPHAR	3634
BindingDB	50023198
DrugBank	DB01411
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
219387	Cysteinyl leukotriene receptor 1	Q2NNR5	CYSLTR1	Cavia porcellus (Guinea pig)	340
219388	Cysteinyl leukotriene receptor 1	Q9Y271	CYSLTR1	Homo sapiens (Human)	337
219389	Cysteinyl leukotriene receptor 2	Q9NS75	CYSLTR2	Homo sapiens (Human)	346
219390	Uracil nucleotide/cysteinyl leukotriene receptor	Q13304	GPR17	Homo sapiens (Human)	367

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