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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Dpt-prostaglandin E1
Molecular formula	C22H30O5
IUPAC name	7-[(1R,2R)-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]heptanoic acid
Molecular weight	374.477
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.5
Synonyms	Cyclopentaneheptanoic acid, 2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxo-, (1R-(1alpha,2beta(1E,3R*)))- M&B28767 11-Deoxy-16-phenoxy-17,18,19,20-tetranor-PGE1 7-[(1R,2R)-2-[(E,3R)-3-hydroxy-4-(phenoxy)but-1-enyl]-5-oxocyclopentyl]heptanoic acid GTPL1913 MB 28767 80558-61-8 M&B 28767 UNII-70K4BF31QF D0BN1U MampB 28767 11-Deoxy-16-phenoxy-17,18,19,20-tetranorprostaglandin E1 7-[(1R,2R)-2-[(E,3R)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl]heptanoic acid LS-58019 MB-28767 AC1NSK8W M&B-28767 MampB-28767 70K4BF31QF M&B 28,767 PDSP2_001534 [ Show all ]
Inchi Key	NZGFSDWJUZOAAX-KAVAACISSA-N
Inchi ID	InChI=1S/C22H30O5/c23-18(16-27-19-8-4-3-5-9-19)14-12-17-13-15-21(24)20(17)10-6-1-2-7-11-22(25)26/h3-5,8-9,12,14,17-18,20,23H,1-2,6-7,10-11,13,15-16H2,(H,25,26)/b14-12+/t17-,18+,20+/m0/s1
PubChem CID	5311223
ChEMBL	N/A
IUPHAR	1913
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554439	Prostaglandin E2 receptor EP1 subtype	P34995	PTGER1	Homo sapiens (Human)	402
554441	Prostaglandin E2 receptor EP1 subtype	P35375	Ptger1	Mus musculus (Mouse)	405
554442	Prostaglandin E2 receptor EP1 subtype	P70597	Ptger1	Rattus norvegicus (Rat)	405
554437	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
554446	Prostaglandin E2 receptor EP2 subtype	Q62928	Ptger2	Rattus norvegicus (Rat)	357
554438	Prostaglandin E2 receptor EP3 subtype	P30557	Ptger3	Mus musculus (Mouse)	365
554443	Prostaglandin E2 receptor EP3 subtype	P34980	Ptger3	Rattus norvegicus (Rat)	365
554445	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
554435	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488
554436	Prostaglandin E2 receptor EP4 subtype	P32240	Ptger4	Mus musculus (Mouse)	513
554440	Prostaglandin E2 receptor EP4 subtype	P43114	Ptger4	Rattus norvegicus (Rat)	488
554444	Prostaglandin F2-alpha receptor	P43117	Ptgfr	Mus musculus (Mouse)	366
554448	Prostaglandin F2-alpha receptor	P43088	PTGFR	Homo sapiens (Human)	359
554447	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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