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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CP-195543
Molecular formula	C24H19F3O4
IUPAC name	2-[(3S,4R)-3-benzyl-4-hydroxy-3,4-dihydro-2H-chromen-7-yl]-4-(trifluoromethyl)benzoic acid
Molecular weight	428.407
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	5.1
Synonyms	D0MM2K SCHEMBL896066 LB4 antagonist (inflammation), Pfizer (3S, 4R)-2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoicacid CHEMBL301829 Leukotriene B4 antagonist (rheumatoid arthritis), Pfizer 2-[(3S,4R)-4-hydroxy-3-(phenylmethyl)chroman-7-yl]-4-(trifluoromethyl)benzoic acid DB13053 UNII-YB1F0V77MK BDBM50215854 LB4 antagonist (RA), Pfizer (3S,4R)-2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid CP 195543 CP195543 NZQDWKCNBOELAI-KSFYIVLOSA-N 204981-48-6 GTPL6155 YB1F0V77MK (3S, 4R)-2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoic acid Benzoic acid, 2-((3S,4R)-3,4-dihydro-4-hydroxy-3-(phenylmethyl)-2H-1-benzopyran-7-yl)-4-(trifluoromethyl)- Leukotriene B4 antagonist (inflammation), Pfizer (3S,4R)-2-(3-benzyl-4-hydroxy-chroman-7-yl)-4-trifluoromethyl-benzoicacid CP-195,543 [ Show all ]
Inchi Key	NZQDWKCNBOELAI-KSFYIVLOSA-N
Inchi ID	InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1
PubChem CID	9823886
ChEMBL	N/A
IUPHAR	6155
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
554450	Leukotriene B4 receptor 1	Q15722	LTB4R	Homo sapiens (Human)	352
554449	Leukotriene B4 receptor 2	Q9NPC1	LTB4R2	Homo sapiens (Human)	358

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