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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL222188
Molecular formula	C26H35N3O
IUPAC name	6-(4-phenylpiperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Molecular weight	405.586
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.5
Synonyms	6-(4-phenylpiperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide BDBM21372 Piperazinehexanamide derivative, 10
Inchi Key	OPNMLXKOFJADTH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H35N3O/c30-26(27-25-15-9-11-22-10-6-7-14-24(22)25)16-5-2-8-17-28-18-20-29(21-19-28)23-12-3-1-4-13-23/h1,3-4,6-7,10,12-14,25H,2,5,8-9,11,15-21H2,(H,27,30)
PubChem CID	11431530
ChEMBL	CHEMBL222188
IUPHAR	N/A
BindingDB	21372
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
247205	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
247208	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
247207	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
247209	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
247210	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
247206	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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