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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431134
Molecular formula	C26H26N4O2
IUPAC name	6,7-dimethoxy-2-phenyl-4-(4-phenylpiperazin-1-yl)quinazoline
Molecular weight	426.52
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	5.2
Synonyms	BDBM50440747 ZINC2338076 488725-39-9 MCULE-5431182931 AC1LZKTC SCHEMBL15819480 MLS-0454790.0001 AKOS022115923 STL333910 6,7-dimethoxy-2-phenyl-4-(4-phenylpiperazin-1-yl)quinazoline MolPort-000-810-051 [ Show all ]
Inchi Key	OPQWCRILQBQTND-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26N4O2/c1-31-23-17-21-22(18-24(23)32-2)27-25(19-9-5-3-6-10-19)28-26(21)30-15-13-29(14-16-30)20-11-7-4-8-12-20/h3-12,17-18H,13-16H2,1-2H3
PubChem CID	1951822
ChEMBL	CHEMBL2431134
IUPHAR	N/A
BindingDB	50440747
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
247282	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
247283	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
247284	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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