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Ligand

NameD0V8NS
Molecular formulaC25H30N2O3
IUPAC name2-[2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl]-4,4-dimethylnaphthalene-1,3-dione
Molecular weight406.526
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP4.2
SynonymsGTPL524
BDBM81772
CAS_122211
NSC_122211
2-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-4,4-dimethyl-1,2,3,4-tetrahydronaphthalene-1,3-dione
Inchi KeyOSEADGVOKYGIER-UHFFFAOYSA-N
Inchi IDInChI=1S/C25H30N2O3/c1-25(2)20-9-5-4-8-18(20)23(28)19(24(25)29)12-13-26-14-16-27(17-15-26)21-10-6-7-11-22(21)30-3/h4-11,19H,12-17H2,1-3H3
PubChem CID122211
ChEMBLN/A
IUPHAR524
BindingDB81772
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 11
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
249098Alpha-2A adrenergic receptorQ28838ADRA2ABos taurus (Bovine)452
249100Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
249104Alpha-2A adrenergic receptorP22909Adra2aRattus norvegicus (Rat)450
249106Alpha-2A adrenergic receptorP18871ADRA2ASus scrofa (Pig)450
249097Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
249099Alpha-2B adrenergic receptorO77830ADRA2BOryctolagus cuniculus (Rabbit)394
249103Alpha-2B adrenergic receptorO77715ADRA2BDidelphis virginiana (North American opossum)382
249107Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
249101Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
249102Alpha-2C adrenergic receptorP35405ADRA2CDidelphis virginiana (North American opossum)469
249108Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458

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