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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL222477
Molecular formula	C26H34ClN3O
IUPAC name	6-[4-(2-chlorophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Molecular weight	440.028
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.1
Synonyms	Piperazinehexanamide derivative, 12 6-[4-(2-chlorophenyl)piperazin-1-yl]-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide BDBM21374
Inchi Key	OVYNZBZCWFALNG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H34ClN3O/c27-23-12-5-6-14-25(23)30-19-17-29(18-20-30)16-7-1-2-15-26(31)28-24-13-8-10-21-9-3-4-11-22(21)24/h3-6,9,11-12,14,24H,1-2,7-8,10,13,15-20H2,(H,28,31)
PubChem CID	11385992
ChEMBL	CHEMBL222477
IUPHAR	N/A
BindingDB	21374
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
251642	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
251646	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
251647	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
251643	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
251644	5-hydroxytryptamine receptor 7	P50407	HTR7	Cavia porcellus (Guinea pig)	446
251645	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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