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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	LOSARTAN POTASSIUM
Molecular formula	C22H22ClKN6O
IUPAC name	potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol
Molecular weight	461.007
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	None
Synonyms	MLS001304723 AS-13609 HMS3373P19 OXCMYAYHXIHQOA-UHFFFAOYSA-N Cozaar KS-1081 losartan potassium salt AKOS015994707 Epoetin MolPort-002-885-836 HY-17512A SMR000550484 124750-99-8 CS-2117 Losartan (potassium) MLS001165733 AKOS025147310 HMS2234C14 MolPort-023-276-936 CHEMBL995 Hyzaar 2-Butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol potassium salt DuP-753 [ Show all ]
Inchi Key	OXCMYAYHXIHQOA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
PubChem CID	11476710
ChEMBL	CHEMBL995
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
252370	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359
252373	Type-1 angiotensin II receptor	P25104	AGTR1	Bos taurus (Bovine)	359
252374	Type-1 angiotensin II receptor	Q9WV26	AGTR1	Cavia porcellus (Guinea pig)	359
252372	Type-1B angiotensin II receptor	P29089	Agtr1b	Rattus norvegicus (Rat)	359
252369	Type-2 angiotensin II receptor	P50052	AGTR2	Homo sapiens (Human)	363
252371	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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