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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1259172
Molecular formula	C25H30FN5O
IUPAC name	1-[2-[4-[5-(aminomethyl)-1-(4-fluorophenyl)indol-3-yl]piperidin-1-yl]ethyl]imidazolidin-2-one
Molecular weight	435.547
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	2.3
Synonyms	1-(2-(4-(5-(aminomethyl)-1-(4-fluorophenyl)-1H-indol-3-yl)piperidin-1-yl)ethyl)imidazolidin-2-one SCHEMBL6581419 BDBM50328474 L020540 1-[2-[4-[5-aminomethyl-1-(4-fluorophenyl)-1H-indol-3-yl]-1-piperidinyl]ethyl]-2-imidazolidinon PBYSLXLVOFLVAY-UHFFFAOYSA-N [ Show all ]
Inchi Key	PBYSLXLVOFLVAY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H30FN5O/c26-20-2-4-21(5-3-20)31-17-23(22-15-18(16-27)1-6-24(22)31)19-7-10-29(11-8-19)13-14-30-12-9-28-25(30)32/h1-6,15,17,19H,7-14,16,27H2,(H,28,32)
PubChem CID	9932698
ChEMBL	CHEMBL1259172
IUPHAR	N/A
BindingDB	50328474
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
256040	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
256041	Alpha-1A adrenergic receptor	P18130	ADRA1A	Bos taurus (Bovine)	466
256039	Alpha-1B adrenergic receptor	P18841	ADRA1B	Mesocricetus auratus (Golden hamster)	515
256043	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
256044	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
256042	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487

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