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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1256748
Molecular formula	C22H32N2O2
IUPAC name	N-methyl-2-phenyl-N-[(5S,7S,8S)-8-pyrrolidin-1-yl-1-oxaspiro[4.5]decan-7-yl]acetamide
Molecular weight	356.51
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.0
Synonyms	BDBM50381677
Inchi Key	PGJPPWQHDNODBR-JAXLGGSGSA-N
Inchi ID	InChI=1S/C22H32N2O2/c1-23(21(25)16-18-8-3-2-4-9-18)20-17-22(11-7-15-26-22)12-10-19(20)24-13-5-6-14-24/h2-4,8-9,19-20H,5-7,10-17H2,1H3/t19-,20-,22+/m0/s1
PubChem CID	52947240
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50381677
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
259092	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
259097	Delta-type opioid receptor	P32300	Oprd1	Mus musculus (Mouse)	372
259099	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
259091	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
259093	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
259096	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
259090	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
259094	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398
259095	Mu-type opioid receptor	P97266	OPRM1	Cavia porcellus (Guinea pig)	98
259101	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
259098	Nociceptin receptor	P47748	OPRL1	Cavia porcellus (Guinea pig)	370
259100	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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