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Ligand

Nametrazodone
Molecular formulaC19H22ClN5O
IUPAC name2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-[1,2,4]triazolo[4,3-a]pyridin-3-one
Molecular weight371.869
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP2.8
SynonymsTrazodon
19794-93-5
Trazodonum
Beneficat
Desirel
[ Show all ]
Inchi KeyPHLBKPHSAVXXEF-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H22ClN5O/c20-16-5-3-6-17(15-16)23-13-11-22(12-14-23)8-4-10-25-19(26)24-9-2-1-7-18(24)21-25/h1-3,5-7,9,15H,4,8,10-14H2
PubChem CID5533
ChEMBLCHEMBL621
IUPHAR213
BindingDB50073444
DrugBankDB00656

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 47
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
2598505-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
2598705-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
2598725-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
2598935-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
2598815-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
2598915-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
2598555-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2598635-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
2598785-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
2598575-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
2598795-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
2598625-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
2598695-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
259867Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
259885Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
259859Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
259864Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
259849Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
259888Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
259858Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462

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