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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1922000
Molecular formula	C27H32F3N7O
IUPAC name	N-(4-methoxyphenyl)-6-piperidin-1-yl-2-[4-[3-(trifluoromethyl)pyridin-2-yl]-1,4-diazepan-1-yl]pyrimidin-4-amine
Molecular weight	527.596
Hydrogen bond acceptor	11
Hydrogen bond donor	1
XlogP	5.9
Synonyms	BDBM50358659 SCHEMBL10144202
Inchi Key	PJVQMHBMXWZOOP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H32F3N7O/c1-38-21-10-8-20(9-11-21)32-23-19-24(35-13-3-2-4-14-35)34-26(33-23)37-16-6-15-36(17-18-37)25-22(27(28,29)30)7-5-12-31-25/h5,7-12,19H,2-4,6,13-18H2,1H3,(H,32,33,34)
PubChem CID	57397798
ChEMBL	CHEMBL1922000
IUPHAR	N/A
BindingDB	50358659
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
261582	Galanin receptor type 1	P47211	GALR1	Homo sapiens (Human)	349
261581	Galanin receptor type 2	O43603	GALR2	Homo sapiens (Human)	387

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