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Ligand

NameDSLET
Molecular formulaC33H46N6O10
IUPAC name(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoic acid
Molecular weight686.763
Hydrogen bond acceptor11
Hydrogen bond donor10
XlogP-3.0
SynonymsDislet
DSTLE
2-Ser-thr-leu-enkephalin
75644-90-5
Tyr-ser-gly-phe-leu-thr
[ Show all ]
Inchi KeyPKSODCLCMBUCPW-LVNBQDLPSA-N
Inchi IDInChI=1S/C33H46N6O10/c1-18(2)13-24(32(47)39-28(19(3)41)33(48)49)37-31(46)25(15-20-7-5-4-6-8-20)36-27(43)16-35-30(45)26(17-40)38-29(44)23(34)14-21-9-11-22(42)12-10-21/h4-12,18-19,23-26,28,40-42H,13-17,34H2,1-3H3,(H,35,45)(H,36,43)(H,37,46)(H,38,44)(H,39,47)(H,48,49)/t19-,23+,24+,25+,26-,28+/m1/s1
PubChem CID107847
ChEMBLCHEMBL124283
IUPHAR1609
BindingDB50018708
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has more than 5 hydrogen bond donor.
This ligand has more than 10 hydrogen bond acceptor.
This ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
262187Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
262188Delta-type opioid receptorP33533Oprd1Rattus norvegicus (Rat)372
262192Delta-type opioid receptorP32300Oprd1Mus musculus (Mouse)372
461490Delta-type opioid receptorP79291OPRD1Sus scrofa (Pig)228
262190Kappa-type opioid receptorP41144OPRK1Cavia porcellus (Guinea pig)380
262191Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
262185Mu-type opioid receptorP42866Oprm1Mus musculus (Mouse)398
262186Mu-type opioid receptorP33535Oprm1Rattus norvegicus (Rat)398
262189Mu-type opioid receptorP97266OPRM1Cavia porcellus (Guinea pig)98
554577Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400

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