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Ligand

NameFLUPHENAZINE
Molecular formulaC22H26F3N3OS
IUPAC name2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol
Molecular weight437.525
Hydrogen bond acceptor8
Hydrogen bond donor1
XlogP4.4
SynonymsTriflumethazine
Fluorophenazine
Fluorphenazine
Fluorfenazine
Siqualon
[ Show all ]
Inchi KeyPLDUPXSUYLZYBN-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H26F3N3OS/c23-22(24,25)17-6-7-21-19(16-17)28(18-4-1-2-5-20(18)30-21)9-3-8-26-10-12-27(13-11-26)14-15-29/h1-2,4-7,16,29H,3,8-15H2
PubChem CID3372
ChEMBLCHEMBL726
IUPHAR204
BindingDB78433
DrugBankDB00623

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 49
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
2625095-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
2625195-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
2625065-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
2625015-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5564965-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2624975-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
2624855-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
2624945-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
2624845-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
2625085-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
5545785-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
5545795-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
452049Adenosine receptor A3P0DMS8ADORA3Homo sapiens (Human)318
452048Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
556500Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
262512Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
262513Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
262479Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
262515Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
262520Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453

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