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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL495737
Molecular formula	C29H38ClN5O3
IUPAC name	[1-[1-[4-[2-(4-chlorophenyl)ethylamino]-6,7-dimethoxyquinazolin-2-yl]piperidin-4-yl]piperidin-3-yl]methanol
Molecular weight	540.105
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	5.5
Synonyms	BDBM50265749 1''-(4-{[2-(4-Chlorophenyl)ethyl]amino}-6,7-dimethoxyquinazolin-2-yl)-1,40-bipiperidin-3-yl]methanol
Inchi Key	PTAGCXBAEBBEDM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C29H38ClN5O3/c1-37-26-16-24-25(17-27(26)38-2)32-29(33-28(24)31-12-9-20-5-7-22(30)8-6-20)34-14-10-23(11-15-34)35-13-3-4-21(18-35)19-36/h5-8,16-17,21,23,36H,3-4,9-15,18-19H2,1-2H3,(H,31,32,33)
PubChem CID	44581103
ChEMBL	CHEMBL495737
IUPHAR	N/A
BindingDB	50265749
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
268166	C-C chemokine receptor type 4	P51679	CCR4	Homo sapiens (Human)	360
268167	C-C chemokine receptor type 4	P51680	Ccr4	Mus musculus (Mouse)	360

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