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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431128
Molecular formula	C24H26N4O3
IUPAC name	6-cyclobutyl-8-[4-(2-methoxyphenyl)piperazin-1-yl]-[1,3]dioxolo[4,5-g]quinazoline
Molecular weight	418.497
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.5
Synonyms	BDBM50440755 MLS-0463414.0001 SCHEMBL15824812
Inchi Key	PWJIZHGNECXEFM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26N4O3/c1-29-20-8-3-2-7-19(20)27-9-11-28(12-10-27)24-17-13-21-22(31-15-30-21)14-18(17)25-23(26-24)16-5-4-6-16/h2-3,7-8,13-14,16H,4-6,9-12,15H2,1H3
PubChem CID	53245574
ChEMBL	CHEMBL2431128
IUPHAR	N/A
BindingDB	50440755
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
270517	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
270515	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
270516	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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