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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SR-48527
Molecular formula	C29H29ClN4O5
IUPAC name	(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid
Molecular weight	549.024
Hydrogen bond acceptor	7
Hydrogen bond donor	2
XlogP	6.0
Synonyms	(2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid D05HYV SCHEMBL18983298 SR48527 (2S)-2-[[1-(7-chloroquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-2-cyclohexylacetic acid. GTPL1581 SR 48527 CHEMBL461604 156579-04-3 S-225 BDBM82417 [ Show all ]
Inchi Key	PXNTUYAGLGTUKX-MHZLTWQESA-N
Inchi ID	InChI=1S/C29H29ClN4O5/c1-38-24-9-6-10-25(39-2)26(24)23-16-21(28(35)32-27(29(36)37)17-7-4-3-5-8-17)33-34(23)22-13-14-31-20-15-18(30)11-12-19(20)22/h6,9-17,27H,3-5,7-8H2,1-2H3,(H,32,35)(H,36,37)/t27-/m0/s1
PubChem CID	9915499
ChEMBL	CHEMBL461604
IUPHAR	1581
BindingDB	82417
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
271473	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
271475	Neurotensin receptor type 1	P20789	Ntsr1	Rattus norvegicus (Rat)	424
271474	Neurotensin receptor type 2	Q63384	Ntsr2	Rattus norvegicus (Rat)	416

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