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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Ethoxyidazoxan
Molecular formula	C13H16N2O3
IUPAC name	2-(3-ethoxy-2H-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole
Molecular weight	248.282
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	0.8
Synonyms	2-(2-Ethoxy-1,4-benzodioxan-2-yl)-1-imidazoline AC1Q70OK SCHEMBL10804432 2-(3-ethoxy-2H-1,4-benzodioxin-3-yl)-4,5-dihydro-1H-imidazole CAS_125992 PDSP1_001655 1H-Imidazole, 2-(2-ethoxy-2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro- 96576-25-9 (hydrochloride) D0R2HZ RX-811059 2-(2-ethoxy-2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1h-imidazole AKOS027322320 L009680 CHEMBL1196898 PDSP2_001639 2-(2-(2-Ethoxy-1,4-benzodioxanyl))-2-imidazoline hydrochloride AC1L2PKE ETHOXY-IDAZOXAN RX-811059A 2-(2-ethoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1h -imidazole BDBM81803 NSC_125992 96576-24-8 CTK8D7107 RX 811033 [ Show all ]
Inchi Key	PXTLRBYNGGDZBN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H16N2O3/c1-2-17-13(12-14-7-8-15-12)9-16-10-5-3-4-6-11(10)18-13/h3-6H,2,7-9H2,1H3,(H,14,15)
PubChem CID	125992
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81803
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
271642	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
271641	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453

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