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Ligand

NameCHEMBL3946540
Molecular formulaC21H25ClN2O2
IUPAC name(2S)-2-[(3-chlorophenoxy)methyl]-4-[2-(2,3-dihydroindol-1-yl)ethyl]morpholine
Molecular weight372.893
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP4.1
SynonymsSCHEMBL14060270
QAJBOIGVHPCSNX-FQEVSTJZSA-N
BDBM186935
US9079895, 23s
(S)-2-((3-chlorophenoxy)methyl)-4-(2-(indolin-1-yl)ethyl)morpholine
Inchi KeyQAJBOIGVHPCSNX-FQEVSTJZSA-N
Inchi IDInChI=1S/C21H25ClN2O2/c22-18-5-3-6-19(14-18)26-16-20-15-23(12-13-25-20)10-11-24-9-8-17-4-1-2-7-21(17)24/h1-7,14,20H,8-13,15-16H2/t20-/m0/s1
PubChem CID71061709
ChEMBLCHEMBL3946540
IUPHARN/A
BindingDB186935
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 12
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5433315-hydroxytryptamine receptor 1AQ64264Htr1aMus musculus (Mouse)421
5433425-hydroxytryptamine receptor 1DQ61224Htr1dMus musculus (Mouse)374
5433355-hydroxytryptamine receptor 2AP35363Htr2aMus musculus (Mouse)471
5433385-hydroxytryptamine receptor 2BQ02152Htr2bMus musculus (Mouse)479
5433325-hydroxytryptamine receptor 2CP34968Htr2cMus musculus (Mouse)459
543337Alpha-1A adrenergic receptorP97718Adra1aMus musculus (Mouse)466
543341Alpha-1B adrenergic receptorP97717Adra1bMus musculus (Mouse)514
543333Alpha-1D adrenergic receptorP97714Adra1dMus musculus (Mouse)562
543340D(1A) dopamine receptorQ61616Drd1Mus musculus (Mouse)446
543334D(2) dopamine receptorP61168Drd2Mus musculus (Mouse)444
543339D(3) dopamine receptorP30728Drd3Mus musculus (Mouse)446
543336D(4) dopamine receptorP51436Drd4Mus musculus (Mouse)387

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