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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2431136
Molecular formula	C26H25FN4O2
IUPAC name	4-[4-(4-fluorophenyl)piperazin-1-yl]-6,7-dimethoxy-2-phenylquinazoline
Molecular weight	444.51
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	5.3
Synonyms	MolPort-000-828-158 BDBM50440745 ZINC2326665 4-[4-(4-fluorophenyl)piperazin-1-yl]-6,7-dimethoxy-2-phenylquinazoline MCULE-2879453052 AC1LZ4L5 SCHEMBL15821039 488096-38-4 MLS-0454796.0001 AKOS005542119 STK606031 [ Show all ]
Inchi Key	QJSSVXHQDQGEIJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H25FN4O2/c1-32-23-16-21-22(17-24(23)33-2)28-25(18-6-4-3-5-7-18)29-26(21)31-14-12-30(13-15-31)20-10-8-19(27)9-11-20/h3-11,16-17H,12-15H2,1-2H3
PubChem CID	1941471
ChEMBL	CHEMBL2431136
IUPHAR	N/A
BindingDB	50440745
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
279997	G-protein coupled receptor 35	Q9HC97	GPR35	Homo sapiens (Human)	309
279996	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418
279995	Neurotensin receptor type 2	O95665	NTSR2	Homo sapiens (Human)	410

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